CCDC90B

Across TCGA patient cohorts, CCDC90B mutation is significantly associated with the RNA expression of many other genes, with 396 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC90B-associated genes across cancer lineages are RN7SKP221, MRPS21P8, and KRTAP20-3. Each is linked with CCDC90B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC90B-to-partner and partner-to-CCDC90B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP221 grouped by CCDC90B-low versus CCDC90B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC90B→partner) and Y-score (partner→CCDC90B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	2
BRCA	MRPS21P8 →	+0.275	+5.575	.003	.004	3	2
UCEC	KRTAP20-3 →	+0.090	+4.738	<.001	.002	3	2
UCEC	CCL27 →	+0.037	+4.148	<.001	.006	3	2
UCEC	ARPP19P1 →	+0.183	+3.418	<.001	<.001	3	2
UCEC	IGHD4-4 →	+0.712	+3.641	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 396 associations by consensus.

RN7SKP221 by CCDC90B expression — BRCA

Explore this box plot interactively →