CCDC89

Across TCGA patient cohorts, CCDC89 mutation is significantly associated with the RNA expression of many other genes, with 405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC89-associated genes across cancer lineages are CYP3A54P, GAPDHP19, and RNU6-841P. Each is linked with CCDC89 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC89-to-partner and partner-to-CCDC89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP3A54P grouped by CCDC89-low versus CCDC89-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC89→partner) and Y-score (partner→CCDC89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CYP3A54P →	+0.413	+7.640	<.001	.009	3	2
BRCA	GAPDHP19 →	+0.044	+5.020	.001	.009	3	2
LUAD	RNU6-841P →	+0.304	+5.011	<.001	.002	3	2
LUAD	RNU6-1144P →	+0.305	+4.590	<.001	.004	3	2
LUAD	LINC01399 →	+0.453	+3.474	<.001	.008	3	2
UCEC	NCAPH2 →	+0.412	+2.169	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 405 associations by consensus.

CYP3A54P by CCDC89 expression — BLCA

Explore this box plot interactively →