CCDC88C

Across TCGA patient cohorts, CCDC88C protein abundance is significantly associated with the RNA expression of many other genes, with 13,171 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC88C-associated genes across cancer lineages are RHOQ, FBXO17, and DRP2. Each is linked with CCDC88C in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC88C-to-partner and partner-to-CCDC88C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC88C versus RHOQ in BRCA, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88C→partner) and Y-score (partner→CCDC88C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RHOQ →	-0.525	-0.398	<.001	<.001	3	6
LSCC	FBXO17 →	-0.927	-0.312	<.001	.007	3	6
PDAC	DRP2 →	-0.624	-0.353	.001	.001	3	5
CCRCC	IGDCC4 →	-0.868	-0.206	<.001	.004	3	5
HNSC	CCDC92 →	-0.539	-0.286	.001	.001	3	5
UCEC	TUB →	-0.918	-0.257	.004	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,171 associations by consensus.

CCDC88C vs RHOQ — BRCA

Explore this scatter interactively →