CCDC88C

Across TCGA patient cohorts, CCDC88C mutation is significantly associated with the RNA expression of many other genes, with 7,496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC88C-associated genes across cancer lineages are CHAC2, FH, and HNRNPC. Each is linked with CCDC88C in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC88C-to-partner and partner-to-CCDC88C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAC2 grouped by CCDC88C-low versus CCDC88C-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88C→partner) and Y-score (partner→CCDC88C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CHAC2 →	+0.773	+3.338	<.001	.005	3	6
UCEC	FH →	+0.402	+1.657	<.001	<.001	3	5
UCEC	HNRNPC →	+0.362	+1.831	<.001	<.001	3	5
COAD	PSMA3 →	+0.497	+2.615	<.001	.005	2	6
UCEC	GNPNAT1 →	+0.666	+1.667	<.001	<.001	3	5
UCEC	PDHX →	+0.616	+2.587	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,496 associations by consensus.

CHAC2 by CCDC88C expression — STAD

Explore this box plot interactively →