CCDC88C

Across TCGA cell cohorts, CCDC88C mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC88C-associated genes across cancer lineages are AVP, AADACL2, and BCAS2. Each is linked with CCDC88C in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC88C-to-partner and partner-to-CCDC88C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by CCDC88C-low versus CCDC88C-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88C→partner) and Y-score (partner→CCDC88C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	AVP →	+0.078	+4.392	<.001	.004	3	2
BLOOD_Lymphoma	AADACL2 →	+0.010	+4.247	<.001	.004	3	2
BLOOD_Leukemia	BCAS2 →	+0.416	+2.614	.007	.003	3	2
LARGE_INTESTINE	SLC35A3 →	+0.543	+2.158	.004	.004	3	2
BLOOD_Leukemia	NEDD1 →	+0.735	+2.614	.001	.003	3	2
BLOOD_Leukemia	ZNF19 →	+0.483	+2.614	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

AVP by CCDC88C expression — SOFT_TISSUE

Explore this box plot interactively →