CCDC88C

Across TCGA cell cohorts, CCDC88C mutation is significantly associated with the mutation status of many other genes, with 5,958 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC88C-associated genes across cancer lineages are EPHB6, EP300, and ESRP1. Each is linked with CCDC88C in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC88C-to-partner and partner-to-CCDC88C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPHB6 grouped by CCDC88C-low versus CCDC88C-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88C→partner) and Y-score (partner→CCDC88C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	EPHB6 →	+4.022	+3.722	.003	.003	1	6
BLOOD_Leukemia	EP300 →	+2.374	+2.318	<.001	<.001	1	5
BLOOD_Leukemia	ESRP1 →	+2.866	+2.284	.003	.003	1	5
LARGE_INTESTINE	PHF12 →	+3.693	+2.462	<.001	<.001	1	5
BLOOD_Leukemia	BRD4 →	+2.544	+2.119	.006	.006	1	5
BLOOD_Lymphoma	ACAN →	+3.146	+3.584	.001	.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,958 associations by consensus.

EPHB6 by CCDC88C expression — SOFT_TISSUE

Explore this box plot interactively →