CCDC88B

Across TCGA patient cohorts, CCDC88B mutation is significantly associated with the RNA expression of many other genes, with 4,402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC88B-associated genes across cancer lineages are IGHD3-9, CENPU, and GUF1. Each is linked with CCDC88B in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC88B-to-partner and partner-to-CCDC88B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD3-9 grouped by CCDC88B-low versus CCDC88B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88B→partner) and Y-score (partner→CCDC88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IGHD3-9 →	+1.055	+2.570	.004	.009	3	3
COAD	CENPU →	+0.911	+3.348	<.001	.004	3	3
UCEC	GUF1 →	+0.485	+1.840	<.001	<.001	3	3
UCEC	BUB1B →	+0.502	+2.400	.006	<.001	3	3
UCEC	MIS18A →	+0.437	+2.459	.001	<.001	3	3
SKCM	DBF4B →	+0.446	+3.484	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

IGHD3-9 by CCDC88B expression — BLCA

Explore this box plot interactively →