CCDC88B

Across TCGA pan-cancer cohorts, CCDC88B RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCDC88B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC88B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC88B is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, KIRP, and STAD are the cancer types where CCDC88B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC88B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.753	<.001	12	view →
KIRP	Male	All	+1.435	<.001	11	view →
STAD	All	All	+0.915	<.001	7	view →
THCA	All	IV	+1.175	.002	6	view →
LIHC	All	II,III,IV	+0.752	<.001	6	view →
HNSC	All	All	+0.629	.004	5	view →
COAD	All	All	+0.747	.005	4	view →
CHOL	All	All	+1.500	<.001	3	view →
LUSC	All	All	−0.624	<.001	3	view →
LUAD	All	All	−0.417	<.001	3	view →
BRCA	Female	II,III,IV	−0.243	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CCDC88B–KIRC

Open the KIRC breakdown →