CCDC88B

Across TCGA cell cohorts, CCDC88B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,052 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC88B-associated GO terms across cancer lineages are Nuclear chromosome segregation, Response to protozoan, and Defense response to protozoan. Each is linked with CCDC88B in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC88B-to-partner and partner-to-CCDC88B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear chromosome segregation grouped by CCDC88B-low versus CCDC88B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88B→partner) and Y-score (partner→CCDC88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Nuclear chromosome segregation →	-0.086	-1.328	<.001	.003	3	7
LARGE_INTESTINE	Response to protozoan →	+0.382	+0.947	.009	.001	3	7
LARGE_INTESTINE	Defense response to protozoan →	+0.382	+0.947	.009	.001	3	7
BREAST	Antigen processing and presentation of exogenous antigen →	+0.201	+1.221	<.001	.001	3	7
URINARY_TRACT	Antigen processing and presentation of peptide antigen via MHC class I →	+0.141	+1.049	<.001	.002	3	7
BREAST	Antigen processing and presentation of exogenous peptide antigen →	+0.215	+1.532	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,052 associations by consensus.

Nuclear chromosome segregation by CCDC88B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →