CCDC88B

Across TCGA cell cohorts, CCDC88B mutation is significantly associated with the RNA expression of many other genes, with 2,726 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC88B-associated genes across cancer lineages are LRRC3C, WARS2, and C16orf92. Each is linked with CCDC88B in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC88B-to-partner and partner-to-CCDC88B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC3C grouped by CCDC88B-low versus CCDC88B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC88B→partner) and Y-score (partner→CCDC88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LRRC3C →	+0.026	+4.142	.009	.003	3	3
SKIN	WARS2 →	+0.449	+2.451	.003	.009	3	2
SKIN	C16orf92 →	+0.017	+2.830	<.001	.004	3	2
SKIN	ST7L →	+0.430	+2.451	.002	.009	3	2
LUNG_NSCLC_LUAD	CPLX4 →	+0.019	+2.560	.001	.006	3	2
LUNG_NSCLC_LUAD	RAB44 →	+0.068	+3.483	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,726 associations by consensus.

LRRC3C by CCDC88B expression — SOFT_TISSUE

Explore this box plot interactively →