CCDC87

Across TCGA patient cohorts, CCDC87 mutation is significantly associated with the RNA expression of many other genes, with 3,717 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC87-associated genes across cancer lineages are OR4C1P, MED15P1, and HSPA8. Each is linked with CCDC87 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC87-to-partner and partner-to-CCDC87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4C1P grouped by CCDC87-low versus CCDC87-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC87→partner) and Y-score (partner→CCDC87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4C1P →	+0.104	+4.063	.002	.004	3	3
HNSC	MED15P1 →	+0.053	+5.020	<.001	<.001	3	3
UCEC	HSPA8 →	+0.977	+2.971	<.001	<.001	3	3
COAD	C18orf25 →	+0.554	+3.229	.001	.009	3	3
COAD	SKA1 →	+0.890	+3.196	<.001	.009	3	3
COAD	NDC80 →	+0.713	+3.210	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,717 associations by consensus.

OR4C1P by CCDC87 expression — HNSC

Explore this box plot interactively →