CCDC87

Across TCGA pan-cancer cohorts, CCDC87 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CCDC87’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CCDC87 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC87 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, HNSC, and LIHC are the cancer types where CCDC87 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC87 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−1.707	<.001	11	view →
HNSC	Male	IV	+0.601	<.001	11	view →
LIHC	Male	All	+0.343	<.001	8	view →
KICH	Male	All	−0.820	<.001	7	view →
LUAD	Male	All	+0.440	<.001	7	view →
BRCA	All	III,IV	+1.020	<.001	6	view →
LUSC	All	All	+0.534	<.001	5	view →
STAD	Male	II,III,IV	+0.412	<.001	5	view →
COAD	Female	All	−0.163	.006	4	view →
CHOL	Male	All	+0.638	<.001	2	view →
PRAD	All	All	+0.227	.004	2	view →
ESCA	Male	All	+0.425	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CCDC87–THCA

Open the THCA breakdown →