CCDC87

Across TCGA cell cohorts, CCDC87 mutation is significantly associated with the RNA expression of many other genes, with 122 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC87-associated genes across cancer lineages are OR10V1, PTCHD3, and ARL13A. Each is linked with CCDC87 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC87-to-partner and partner-to-CCDC87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by CCDC87-low versus CCDC87-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC87→partner) and Y-score (partner→CCDC87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10V1 →	+0.016	+4.437	<.001	.004	3	3
KIDNEY	PTCHD3 →	+0.006	+5.000	<.001	.005	3	2
LARGE_INTESTINE	ARL13A →	+0.073	+3.369	<.001	.007	3	2
LARGE_INTESTINE	FAM205A →	+0.020	+2.444	<.001	.008	3	2
BLOOD_Leukemia	FBXW10 →	+0.052	+3.125	<.001	<.001	3	2
BLOOD_Leukemia	IQCF5 →	+0.032	+2.786	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 122 associations by consensus.

OR10V1 by CCDC87 expression — SKIN

Explore this box plot interactively →