CCDC86

Across TCGA pan-cancer cohorts, CCDC86 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC86 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC86 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC86 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where CCDC86 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.799	0.981	.009	46	view →
LUAD	DFS	Median	II,III,IV	0.773	1.000	.005	8	view →
LSCC	DFS	Median	II,III,IV	0.853	0.528	.008	5	view →
HNSC	DFS	Median	III,IV	0.687	0.885	.006	4	view →
PDAC	OS	Median	III,IV	0.446	0.732	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC86–CCRCC (OS)

Open the CCRCC breakdown →