CCDC86

Across TCGA patient cohorts, CCDC86 mutation is significantly associated with the RNA expression of many other genes, with 1,639 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC86-associated genes across cancer lineages are RNA5SP426, OR12D1, and MIR7702. Each is linked with CCDC86 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC86-to-partner and partner-to-CCDC86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP426 grouped by CCDC86-low versus CCDC86-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC86→partner) and Y-score (partner→CCDC86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP426 →	+0.318	+7.924	<.001	.008	3	3
READ	OR12D1 →	+0.081	+5.257	<.001	.002	3	2
UCEC	MIR7702 →	+0.202	+4.060	<.001	.006	3	2
LUAD	RN7SL341P →	+0.150	+4.990	<.001	.009	3	2
UCEC	TAF11L12 →	+0.271	+2.174	.003	.002	3	2
UCEC	RNA5SP413 →	+0.979	+1.955	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,639 associations by consensus.

RNA5SP426 by CCDC86 expression — LUSC

Explore this box plot interactively →