CCDC86

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC86 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCDC86-associated genes across cancer lineages are ACER1 and OR5P2. Each is linked with CCDC86 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC86-to-partner and partner-to-CCDC86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by CCDC86-low versus CCDC86-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC86→partner) and Y-score (partner→CCDC86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEACER1 →+0.081+3.823.004.00631
BLOOD_LymphomaOR5P2 →+0.018+4.867.001.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ACER1 by CCDC86 expression — LARGE_INTESTINE

Box plot of ACER1 in CCDC86-low vs CCDC86-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration