CCDC85B

Across TCGA pan-cancer cohorts, CCDC85B mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC85B data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CCDC85B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC85B expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

UCEC, LUAD, and GBM are the cancer types where CCDC85B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.567	1.000	.008	20	view →
LUAD	DFS	Tertile	All	0.906	0.387	.009	18	view →
GBM	OS	Tertile	All	0.669	0.362	.006	9	view →
PDAC	DFS	Quartile	II,III,IV	0.504	0.162	.012	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC85B–UCEC (OS)

Open the UCEC breakdown →