CCDC85B

Across TCGA pan-cancer cohorts, CCDC85B RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CCDC85B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCDC85B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC85B is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.

COAD, BLCA, and KIRC are the cancer types where CCDC85B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC85B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+2.024	<.001	11	view →
BLCA	All	All	−0.933	<.001	10	view →
KIRC	Female	All	+1.022	<.001	9	view →
LIHC	Female	All	+1.101	<.001	7	view →
UCEC	All	All	−0.670	.010	6	view →
ESCA	All	All	+0.926	.005	4	view →
LUAD	All	All	−0.632	<.001	4	view →
THCA	All	All	+0.438	.020	4	view →
HNSC	Male	III,IV	+0.878	.023	2	view →
LUSC	Female	All	−0.804	.017	2	view →
STAD	Male	II,III,IV	+0.707	.005	2	view →
READ	All	All	+1.064	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CCDC85B–COAD

Open the COAD breakdown →