CCDC85B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC85B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CCDC85B-associated genes across cancer lineages are RNU7-159P, RNU6-176P, and NDUFA5P6. Each is linked with CCDC85B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC85B-to-partner and partner-to-CCDC85B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-159P grouped by CCDC85B-low versus CCDC85B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC85B→partner) and Y-score (partner→CCDC85B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU7-159P →+1.798+5.435<.001.00531
COADRNU6-176P →+0.607+5.080<.001.00831
COADNDUFA5P6 →+0.353+5.212<.001.00731
COADNXF2B →+0.022+6.547<.001.00131
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RNU7-159P by CCDC85B expression — COAD

Box plot of RNU7-159P in CCDC85B-low vs CCDC85B-high samples in COAD.

Explore this box plot interactively →

Exploration