CCDC85B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC85B mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC85B-associated genes across cancer lineages are EPPIN, OR10G3, and C14orf177. Each is linked with CCDC85B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC85B-to-partner and partner-to-CCDC85B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by CCDC85B-low versus CCDC85B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC85B→partner) and Y-score (partner→CCDC85B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaEPPIN →+0.006+4.922.005.00931
BLOOD_LeukemiaOR10G3 →+0.025+5.201<.001.00631
BLOOD_LeukemiaC14orf177 →+0.100+4.922<.001.00931
BLOOD_LeukemiaNKX2-6 →+0.639+5.201<.001.00631
BLOOD_LeukemiaOR52E4 →+0.012+5.201.008.00631
BLOOD_LeukemiaOC90 →+0.013+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

EPPIN by CCDC85B expression — BLOOD_Leukemia

Box plot of EPPIN in CCDC85B-low vs CCDC85B-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration