CCDC85A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCDC85A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC85A data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CCDC85A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC85A expression acts as an unfavorable survival marker.

PDAC, LUAD, and LSCC are the cancer types where CCDC85A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.4930.835.00239view →
LUADDFSQuartileAll0.8181.000.00312view →
LSCCDFSMedianAll0.8840.980.0241view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCDC85A–PDAC (DFS)

Kaplan–Meier survival curve for CCDC85A mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration