CCDC85A

Across TCGA patient cohorts, CCDC85A mutation is significantly associated with the RNA expression of many other genes, with 2,556 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC85A-associated genes across cancer lineages are HAUS2, RNU2-71P, and UBE2Q2P2. Each is linked with CCDC85A in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC85A-to-partner and partner-to-CCDC85A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAUS2 grouped by CCDC85A-low versus CCDC85A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC85A→partner) and Y-score (partner→CCDC85A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HAUS2 →	+0.493	+2.081	<.001	<.001	3	4
CESC	RNU2-71P →	+0.162	+4.384	<.001	.008	3	3
SKCM	UBE2Q2P2 →	+0.631	+2.706	.001	.003	3	3
HNSC	RNU7-110P →	+0.413	+2.660	<.001	.004	3	3
READ	CHCHD2P1 →	+0.160	+4.533	.002	.004	3	3
HNSC	YTHDF2 →	+0.412	+3.356	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,556 associations by consensus.

HAUS2 by CCDC85A expression — UCEC

Explore this box plot interactively →