CCDC85A

Across TCGA cell cohorts, CCDC85A mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC85A-associated genes across cancer lineages are LEUTX, MBD3L2, and RBMY1J. Each is linked with CCDC85A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC85A-to-partner and partner-to-CCDC85A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEUTX grouped by CCDC85A-low versus CCDC85A-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC85A→partner) and Y-score (partner→CCDC85A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LEUTX →	+0.062	+3.817	<.001	.004	3	2
LUNG_SCLC	MBD3L2 →	+0.617	+3.523	<.001	.008	3	2
SOFT_TISSUE	RBMY1J →	+0.035	+4.930	<.001	.008	3	1
SOFT_TISSUE	RBMY1E →	+1.177	+4.930	<.001	.008	3	1
SOFT_TISSUE	RBMY1B →	+0.726	+4.930	<.001	.008	3	1
LUNG_NSCLC_LUSC	NPVF →	+0.029	+4.108	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

LEUTX by CCDC85A expression — LUNG_SCLC

Explore this box plot interactively →