CCDC81

Across TCGA cell cohorts, CCDC81 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,967 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC81-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Positive regulation of type 2 mitophagy, and Regulation of cell cycle G1/S phase transition. Each is linked with CCDC81 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC81-to-partner and partner-to-CCDC81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by CCDC81-low versus CCDC81-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC81→partner) and Y-score (partner→CCDC81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of calcium ion export across plasma membrane →	+0.062	+0.274	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Positive regulation of type 2 mitophagy →	+0.132	+0.350	.001	.002	3	9
LARGE_INTESTINE	Regulation of cell cycle G1/S phase transition →	+0.046	+0.248	.002	.002	3	8
PANCREAS	Regulation of myoblast fusion →	+0.113	+0.275	<.001	<.001	3	8
PANCREAS	Positive regulation of double-strand break repair →	+0.047	+0.213	.003	.001	3	8
PANCREAS	Regulation of intracellular protein transport →	+0.061	+0.153	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,967 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by CCDC81 expression — LARGE_INTESTINE

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