CCDC8

Across TCGA patient cohorts, CCDC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,983 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCDC8-associated proteins across cancer lineages are CCDC8_S261, CCDC8_S202, and CCDC8_S273. Each is linked with CCDC8 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC8-to-partner and partner-to-CCDC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC8 versus CCDC8_S261 in CCRCC, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC8→partner) and Y-score (partner→CCDC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CCDC8_S261 →	+1.023	+2.305	<.001	<.001	3	9
CCRCC	CCDC8_S202 →	+1.262	+2.242	<.001	<.001	3	8
CCRCC	CCDC8_S273 →	+1.848	+2.172	<.001	<.001	3	7
BRCA	MRC2 →	+0.627	+0.888	<.001	<.001	3	6
LSCC	COL3A1 →	+0.665	+1.255	<.001	<.001	3	6
HNSC	FKBP10 →	+0.563	+1.467	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,983 associations by consensus.

CCDC8 vs CCDC8_S261 — CCRCC

Explore this scatter interactively →