CCDC77

Across TCGA patient cohorts, CCDC77 protein abundance is significantly associated with the RNA expression of many other genes, with 9,661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC77-associated genes across cancer lineages are AP4S1, LONP2, and ZNF205. Each is linked with CCDC77 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC77-to-partner and partner-to-CCDC77 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC77 versus AP4S1 in UCEC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC77→partner) and Y-score (partner→CCDC77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AP4S1 →	-0.491	-0.319	.005	.006	3	2
BRCA	LONP2 →	-0.606	-0.315	.009	.003	3	2
LUAD	ZNF205 →	-0.418	-0.303	.002	<.001	3	2
LUAD	EMC8 →	-0.287	-0.257	.002	.001	3	2
BRCA	AKTIP →	-0.511	-0.378	.004	.005	3	2
BRCA	NCBP2L →	-0.637	-0.461	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,661 associations by consensus.

CCDC77 vs AP4S1 — UCEC

Explore this scatter interactively →