CCDC74B

Across TCGA cell cohorts, CCDC74B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,522 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC74B-associated GO terms across cancer lineages are Transport along microtubule, Nucleoside triphosphate metabolic process, and Protein localization to cilium. Each is linked with CCDC74B in more than 14 cancer types. Because this analysis shows association rather than direction, both CCDC74B-to-partner and partner-to-CCDC74B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by CCDC74B-low versus CCDC74B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC74B→partner) and Y-score (partner→CCDC74B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transport along microtubule →	+0.063	+2.275	<.001	<.001	3	15
BONE	Nucleoside triphosphate metabolic process →	+0.089	+1.673	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Protein localization to cilium →	+0.076	+1.501	.001	.006	2	14
OVARY	Microtubule cytoskeleton organization involved in mitosis →	+0.079	+1.134	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome organization →	+0.082	+1.097	.005	.001	3	13
STOMACH	Regulation of chromosome organization →	+0.072	+2.033	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,522 associations by consensus.

Transport along microtubule by CCDC74B expression — BONE

Explore this box plot interactively →