CCDC74B

Across TCGA cell cohorts, CCDC74B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCDC74B-associated genes across cancer lineages are DCSTAMP, LINC02881, and OR13C4. Each is linked with CCDC74B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC74B-to-partner and partner-to-CCDC74B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCSTAMP grouped by CCDC74B-low versus CCDC74B-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC74B→partner) and Y-score (partner→CCDC74B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DCSTAMP →	+0.018	+5.000	.001	.006	3	1
PANCREAS	LINC02881 →	+0.022	+5.000	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR13C4 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	C1QC →	+0.022	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP17-1 →	+0.028	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	MLN →	+0.069	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

DCSTAMP by CCDC74B expression — PANCREAS

Explore this box plot interactively →