CCDC74A

Across TCGA patient cohorts, CCDC74A mutation is significantly associated with the RNA expression of many other genes, with 2,661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC74A-associated genes across cancer lineages are MIR676, GSTA6P, and ZNHIT3. Each is linked with CCDC74A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC74A-to-partner and partner-to-CCDC74A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR676 grouped by CCDC74A-low versus CCDC74A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC74A→partner) and Y-score (partner→CCDC74A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR676 →	+0.211	+4.516	<.001	.004	3	2
CESC	GSTA6P →	+0.068	+3.595	<.001	.005	3	2
UCEC	ZNHIT3 →	+0.404	+2.343	.009	.003	3	2
UCEC	MIR6859-3 →	+0.108	+3.736	<.001	.009	3	2
COAD	MIR5692A1 →	+1.263	+3.515	<.001	.005	3	2
COAD	RN7SL802P →	+0.351	+4.721	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,661 associations by consensus.

MIR676 by CCDC74A expression — CESC

Explore this box plot interactively →