CCDC74A

Across TCGA cell cohorts, CCDC74A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,416 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC74A-associated GO terms across cancer lineages are Intraciliary anterograde transport, Intraciliary transport involved in cilium assembly, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with CCDC74A in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC74A-to-partner and partner-to-CCDC74A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by CCDC74A-low versus CCDC74A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC74A→partner) and Y-score (partner→CCDC74A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Intraciliary anterograde transport →	+0.104	+2.317	<.001	<.001	3	13
CNS	Intraciliary transport involved in cilium assembly →	+0.133	+1.891	<.001	<.001	3	12
OVARY	Microtubule cytoskeleton organization involved in mitosis →	+0.092	+1.928	<.001	<.001	3	12
BREAST	Negative regulation of chromosome organization →	+0.067	+1.490	.005	<.001	3	12
BONE	Transport along microtubule →	+0.066	+2.231	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of mitotic cytokinetic process →	+0.135	+1.580	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,416 associations by consensus.

Intraciliary anterograde transport by CCDC74A expression — LIVER

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