CCDC71

Across TCGA pan-cancer cohorts, CCDC71 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC71 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CCDC71 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC71 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where CCDC71 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.309	0.697	.004	20	view →
LUAD	DFS	Tertile	III,IV	0.829	0.271	.017	7	view →
HNSC	OS	Median	All	0.946	0.697	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCDC71–PDAC (OS)

Open the PDAC breakdown →