CCDC70

Across TCGA patient cohorts, CCDC70 mutation is significantly associated with the RNA expression of many other genes, with 873 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC70-associated genes across cancer lineages are RNU6-102P, RPL35AP30, and LINC02136. Each is linked with CCDC70 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC70-to-partner and partner-to-CCDC70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-102P grouped by CCDC70-low versus CCDC70-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC70→partner) and Y-score (partner→CCDC70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-102P →	+0.279	+9.057	<.001	.003	3	2
LUAD	RPL35AP30 →	+0.238	+3.938	<.001	.003	3	2
LUAD	LINC02136 →	+0.269	+3.841	<.001	.002	3	2
UCEC	LINC01399 →	+0.229	+2.337	<.001	.008	3	2
UCEC	RNU6-1213P →	+0.437	+5.069	<.001	<.001	3	2
SKCM	PDCD5P2 →	+0.128	+2.741	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 873 associations by consensus.

RNU6-102P by CCDC70 expression — BRCA

Explore this box plot interactively →