CCDC70

Across TCGA cell cohorts, CCDC70 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CCDC70-associated genes across cancer lineages are CCL18, GPR101, and OR1L6. Each is linked with CCDC70 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC70-to-partner and partner-to-CCDC70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by CCDC70-low versus CCDC70-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC70→partner) and Y-score (partner→CCDC70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCL18 →	+0.129	+5.415	<.001	.004	3	1
OVARY	GPR101 →	+0.024	+4.990	<.001	.001	3	1
OVARY	OR1L6 →	+0.015	+4.807	<.001	.003	3	1
OVARY	OR4C11 →	+0.015	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.016	+4.029	<.001	.009	3	1
OVARY	OR2H1 →	+0.019	+4.029	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CCL18 by CCDC70 expression — LARGE_INTESTINE

Explore this box plot interactively →