CCDC66

Across TCGA patient cohorts, CCDC66 protein abundance is significantly associated with the RNA expression of many other genes, with 140 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCDC66-associated genes across cancer lineages are KCNT1, HSPA12B, and MAMLD1. Each is linked with CCDC66 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC66-to-partner and partner-to-CCDC66 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC66 versus KCNT1 in PDAC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC66→partner) and Y-score (partner→CCDC66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KCNT1 →	-0.138	-0.527	.001	.001	3	1
PDAC	HSPA12B →	-0.550	-0.441	.002	.006	3	1
PDAC	MAMLD1 →	-0.576	-0.574	.002	.004	3	1
PDAC	PADI1 →	-3.189	-0.521	<.001	.001	3	1
PDAC	CAND2 →	-0.544	-0.630	<.001	<.001	3	1
PDAC	RIT2 →	+0.094	+1.043	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 140 associations by consensus.

CCDC66 vs KCNT1 — PDAC

Explore this scatter interactively →