CCDC63

Across TCGA patient cohorts, CCDC63 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,982 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CCDC63-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, and Mitochondrial gene expression. Each is linked with CCDC63 in more than 14 cancer types. Because this analysis shows association rather than direction, both CCDC63-to-partner and partner-to-CCDC63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of post-translational protein modification grouped by CCDC63-low versus CCDC63-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC63→partner) and Y-score (partner→CCDC63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of post-translational protein modification →	+0.072	+0.165	<.001	.002	3	15
STAD	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.070	+0.196	<.001	<.001	3	15
STAD	Mitochondrial gene expression →	+0.076	+0.232	<.001	<.001	3	14
STAD	Positive regulation of proteasomal protein catabolic process →	+0.070	+0.208	<.001	<.001	3	14
ESCA	Regulation of post-translational protein modification →	+0.075	+0.158	<.001	.002	2	15
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.067	+0.221	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,982 associations by consensus.

Positive regulation of post-translational protein modification by CCDC63 expression — ESCA

Explore this box plot interactively →