CCDC63

Across TCGA cell cohorts, CCDC63 RNA expression is significantly associated with the go_rna of many other GO terms, with 974 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC63-associated GO terms across cancer lineages are Sperm flagellum assembly, Positive regulation of vasculature development, and Negative regulation of transcription initiation-coupled chromatin remodeling. Each is linked with CCDC63 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC63-to-partner and partner-to-CCDC63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm flagellum assembly grouped by CCDC63-low versus CCDC63-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC63→partner) and Y-score (partner→CCDC63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Sperm flagellum assembly →	-0.034	-0.012	<.001	.007	3	5
BONE	Positive regulation of vasculature development →	-0.095	-0.078	.001	.007	3	5
LUNG_SCLC	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.106	+0.295	.003	.006	3	5
LIVER	Positive regulation of protein acetylation →	+0.098	+0.053	.005	.003	3	4
BONE	Regulation of vasculature development →	-0.109	-0.071	<.001	.003	3	4
BONE	Regulation of leukocyte migration →	-0.076	-0.065	.003	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 974 associations by consensus.

Sperm flagellum assembly by CCDC63 expression — SKIN

Explore this box plot interactively →