CCDC63

Across TCGA cell cohorts, CCDC63 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC63-associated genes across cancer lineages are GAPDHS, OR13D1, and RSPH6A. Each is linked with CCDC63 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC63-to-partner and partner-to-CCDC63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDHS grouped by CCDC63-low versus CCDC63-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC63→partner) and Y-score (partner→CCDC63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GAPDHS →	+0.041	+2.748	.009	.004	3	2
URINARY_TRACT	OR13D1 →	+0.032	+4.217	<.001	.005	3	1
LARGE_INTESTINE	RSPH6A →	+0.136	+3.129	<.001	.001	3	1
LARGE_INTESTINE	VSX2 →	+0.014	+2.257	.001	.009	3	1
LARGE_INTESTINE	PLVAP →	+0.182	+2.841	.002	.002	3	1
LARGE_INTESTINE	BRDT →	+0.095	+2.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

GAPDHS by CCDC63 expression — LARGE_INTESTINE

Explore this box plot interactively →