CCDC62

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCDC62 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC62 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CCDC62 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCDC62 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, GBM, and LUAD are the cancer types where CCDC62 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileAll1.0000.695.00713view →
GBMDFSMedianAll0.4060.763.0028view →
LUADOSMedianII,III,IV0.3560.893.0256view →
CCRCCDFSMedianIV0.2220.887.0383view →
LSCCDFSTertileAll0.9211.000.0291view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC62–HNSC (DFS)

Kaplan–Meier survival curve for CCDC62 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration