CCDC62

Across TCGA patient cohorts, CCDC62 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC62-associated genes across cancer lineages are C-Raf, PARP_cleaved, and eEF2. Each is linked with CCDC62 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC62-to-partner and partner-to-CCDC62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by CCDC62-low versus CCDC62-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC62→partner) and Y-score (partner→CCDC62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	C-Raf →	+0.188	+2.459	.004	.020	3	3
COAD	PARP_cleaved →	+0.518	+2.820	.049	.035	3	1
UCEC	eEF2 →	+0.445	+2.459	<.001	.018	3	1
UCEC	EGFR_pY1068 →	-0.298	-1.765	.001	.014	3	1
UCEC	A-Raf_pS299 →	-0.182	-3.321	<.001	.009	3	1
UCEC	FoxM1 →	+0.200	+1.765	.040	.014	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

C-Raf by CCDC62 expression — SKCM

Explore this box plot interactively →