CCDC58P3

Across TCGA pan-cancer cohorts, CCDC58P3 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CCDC58P3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CCDC58P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC58P3 is over-expressed in tumor.

HNSC, LUSC, and BLCA are the cancer types where CCDC58P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC58P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.090	.002	8	view →
LUSC	All	II,III,IV	+0.229	<.001	6	view →
BLCA	Male	III,IV	+0.307	.021	3	view →
COAD	Male	II,III,IV	+0.209	.024	2	view →
LUAD	All	All	+0.108	.005	2	view →
LIHC	All	All	+0.070	.006	2	view →
BRCA	Female	All	+0.069	.024	2	view →
STAD	All	All	+0.159	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CCDC58P3–HNSC

Open the HNSC breakdown →