CCDC47

Across TCGA pan-cancer cohorts, CCDC47 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC47 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC47 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC47 expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

CCRCC, COAD, and PDAC are the cancer types where CCDC47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.491	1.000	.005	38	view →
COAD	DFS	Median	All	1.000	0.888	.023	36	view →
PDAC	OS	Tertile	All	0.269	0.472	.006	5	view →
HNSC	DFS	Median	IV	0.920	1.000	.028	4	view →
LSCC	DFS	Tertile	All	0.557	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC47–CCRCC (OS)

Open the CCRCC breakdown →