CCDC47

Across TCGA pan-cancer cohorts, CCDC47 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CCDC47’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CCDC47 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC47 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

BLCA, HNSC, and LIHC are the cancer types where CCDC47 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC47 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+0.942	<.001	11	view →
HNSC	All	All	+0.415	<.001	10	view →
LIHC	Male	All	+0.815	<.001	9	view →
KICH	Female	All	−1.201	<.001	7	view →
THCA	Male	All	−0.446	<.001	7	view →
STAD	Male	II,III,IV	+0.724	<.001	6	view →
BRCA	All	III,IV	+0.556	<.001	6	view →
LUAD	All	All	+0.320	<.001	5	view →
CHOL	All	All	+1.033	<.001	4	view →
COAD	All	All	−0.239	.023	4	view →
KIRP	Female	II,III,IV	+0.623	.020	3	view →
ESCA	Female	All	+1.239	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CCDC47–BLCA

Open the BLCA breakdown →