CCDC47

Across TCGA cell cohorts, CCDC47 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,195 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC47-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Multi-pass transmembrane protein insertion into ER membrane, and CAAX-box protein maturation. Each is linked with CCDC47 in more than 10 cancer types. Because this analysis shows association rather than direction, both CCDC47-to-partner and partner-to-CCDC47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by CCDC47-low versus CCDC47-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC47→partner) and Y-score (partner→CCDC47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of beige fat cell differentiation →	+0.132	+0.621	.001	<.001	3	11
BLOOD_Lymphoma	Multi-pass transmembrane protein insertion into ER membrane →	+0.100	+0.712	<.001	<.001	3	10
LARGE_INTESTINE	CAAX-box protein maturation →	+0.125	+0.689	<.001	<.001	3	10
LIVER	Response to L-phenylalanine derivative →	+0.160	+0.541	.001	.004	3	9
OVARY	Double-strand break repair via alternative nonhomologous end joining →	+0.105	+0.591	<.001	.004	3	8
BONE	Regulation of microtubule cytoskeleton organization →	+0.051	+0.678	.005	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,195 associations by consensus.

Negative regulation of beige fat cell differentiation by CCDC47 expression — OVARY

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