CCDC43

Across TCGA cell cohorts, CCDC43 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC43-associated genes across cancer lineages are BPIFB6, BTNL2, and MROH5. Each is linked with CCDC43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC43-to-partner and partner-to-CCDC43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by CCDC43-low versus CCDC43-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC43→partner) and Y-score (partner→CCDC43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.025	+5.022	<.001	.002	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MROH5 →	+0.130	+4.467	<.001	.004	3	1
LARGE_INTESTINE	TEX53 →	+0.134	+4.684	<.001	.002	3	1
LARGE_INTESTINE	OR13C7 →	+0.019	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

BPIFB6 by CCDC43 expression — LARGE_INTESTINE

Explore this box plot interactively →