CCDC40

Across TCGA patient cohorts, CCDC40 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,286 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC40-associated proteins across cancer lineages are IFT74, WDR54, and TRAF3IP1. Each is linked with CCDC40 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC40-to-partner and partner-to-CCDC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC40 versus IFT74 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC40→partner) and Y-score (partner→CCDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IFT74 →	+0.430	+1.096	<.001	<.001	3	7
UCEC	WDR54 →	+0.479	+0.905	<.001	<.001	3	6
BRCA	TRAF3IP1 →	+0.452	+0.879	<.001	<.001	3	6
UCEC	IFT57 →	+0.404	+0.734	<.001	<.001	3	6
UCEC	IFT22 →	+0.461	+0.836	<.001	<.001	3	6
UCEC	WDR35 →	+0.364	+0.871	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,286 associations by consensus.

CCDC40 vs IFT74 — GBM

Explore this scatter interactively →