CCDC40

Across TCGA cell cohorts, CCDC40 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,621 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCDC40-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, Transport along microtubule, and Cilium-dependent cell motility. Each is linked with CCDC40 in more than 15 cancer types. Because this analysis shows association rather than direction, both CCDC40-to-partner and partner-to-CCDC40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by CCDC40-low versus CCDC40-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC40→partner) and Y-score (partner→CCDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.076	+1.278	<.001	<.001	3	16
LUNG_SCLC	Transport along microtubule →	+0.074	+1.173	<.001	.001	3	15
OESOPHAGUS	Cilium-dependent cell motility →	-0.106	-1.121	.002	.007	3	14
OESOPHAGUS	Cilium movement involved in cell motility →	-0.110	-1.161	.002	.005	2	15
LARGE_INTESTINE	Sperm motility →	-0.088	-1.087	<.001	<.001	3	14
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.106	-1.121	.002	.007	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,621 associations by consensus.

Cytoskeleton-dependent intracellular transport by CCDC40 expression — LUNG_SCLC

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