CCDC40

Across TCGA cell cohorts, CCDC40 mutation is significantly associated with the RNA expression of many other genes, with 952 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC40-associated genes across cancer lineages are FABP12, NPHS2, and PFN3. Each is linked with CCDC40 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC40-to-partner and partner-to-CCDC40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP12 grouped by CCDC40-low versus CCDC40-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC40→partner) and Y-score (partner→CCDC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FABP12 →	+0.095	+5.643	<.001	.002	3	3
URINARY_TRACT	NPHS2 →	+0.187	+5.044	<.001	<.001	3	2
URINARY_TRACT	PFN3 →	+0.050	+4.087	<.001	.009	3	2
BLOOD_Myeloma	HTR3D →	+0.020	+4.807	<.001	.006	3	2
BLOOD_Leukemia	SPEM3 →	+0.007	+2.824	.003	.007	3	2
BLOOD_Lymphoma	ANKRD33 →	+0.006	+5.643	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 952 associations by consensus.

FABP12 by CCDC40 expression — BLOOD_Lymphoma

Explore this box plot interactively →