CCDC38

Across TCGA cell cohorts, CCDC38 mutation is significantly associated with the RNA expression of many other genes, with 223 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC38-associated genes across cancer lineages are GCAT, CBY1, and TRMU. Each is linked with CCDC38 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC38-to-partner and partner-to-CCDC38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by CCDC38-low versus CCDC38-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC38→partner) and Y-score (partner→CCDC38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.422	+3.364	<.001	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.552	+3.137	.005	.007	3	1
LARGE_INTESTINE	TRMU →	+0.618	+3.364	.001	.002	3	1
LARGE_INTESTINE	CTSZ →	-1.306	-3.278	<.001	.006	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 223 associations by consensus.

GCAT by CCDC38 expression — LARGE_INTESTINE

Explore this box plot interactively →