CCDC37-DT

Across TCGA pan-cancer cohorts, CCDC37-DT RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CCDC37-DT data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CCDC37-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC37-DT expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

BRCA, ACC, and READ are the cancer types where CCDC37-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	III,IV	0.564	0.819	<.001	78	view →
ACC	DFS	Tertile	All	0.262	0.704	<.001	45	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	45	view →
LIHC	OS	Tertile	All	0.515	0.704	.004	42	view →
MESO	DFS	Tertile	III,IV	0.238	0.444	.021	36	view →
LGG	DFS	Quartile	All	0.730	0.876	.002	26	view →
UCEC	DFS	Tertile	IV	0.858	0.348	.024	24	view →
BLCA	OS	Tertile	II,III,IV	0.676	0.404	.025	21	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
PCPG	DFS	Tertile	All	0.079	0.862	<.001	18	view →
KIRC	DFS	Tertile	IV	0.203	0.489	.025	18	view →
ESCA	OS	Tertile	III,IV	0.599	0.317	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CCDC37-DT–BRCA (DFS)

Open the BRCA breakdown →