CCDC33

Across TCGA patient cohorts, CCDC33 mutation is significantly associated with the RNA expression of many other genes, with 2,465 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC33-associated genes across cancer lineages are CINP, NDUFC1, and MTFR1L. Each is linked with CCDC33 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC33-to-partner and partner-to-CCDC33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CINP grouped by CCDC33-low versus CCDC33-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC33→partner) and Y-score (partner→CCDC33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CINP →	+0.313	+2.179	<.001	.008	3	3
SKCM	NDUFC1 →	+0.300	+2.813	<.001	<.001	3	3
SKCM	MTFR1L →	+0.321	+4.012	<.001	<.001	3	3
SKCM	DNAJC8 →	+0.345	+2.247	.003	.005	3	3
UCEC	IL21 →	+0.196	+2.529	<.001	<.001	3	3
LUSC	RPL35AP30 →	+0.083	+2.210	.007	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,465 associations by consensus.

CINP by CCDC33 expression — SKCM

Explore this box plot interactively →